Keren Xu – projects

Investigating DNA methylation as a mediator of genetic risk in childhood acute lymphoblastic Leukemia

epigenome-wide association study, methylation quantitative trait loci, causal mediation

Accelerated Epigenetic Aging in Newborns with Down Syndrome

The Impact of Physician Experience on Decision Aid Efficacy in Severe Aortic Stenosis

Whole-Exome Sequencing in Multiplex Families to Identify Novel AYA Classical Hodgkin Lymphoma Predisposition Genes

Poster presentation at the 63rd American Society of Hematology (ASH) annual meeting and exposition, December 11-14, 2021

Accelerated Epigenetic Aging in Newborns with Down Syndrome

Poster presentation at the (American Society of Human Genetics) ASHG Virtual Meeting, 2021.

Personalized, Electronic Health Record–Integrated Decision Aid for Stroke Prevention in Atrial Fibrillation, A Small Cluster Randomized Trial and Qualitative Analysis of Efficacy and Acceptability

A small cluster randomized trial included 6 cardiovascular clinicians and 66 patients randomized either to the intervention or usual care during a clinical encounter when…

Disparities in acute lymphoblastic leukemia risk and survival across the lifespan in the United States of America

We review the racial/ethnic disparities in ALL incidence and outcomes, discuss how these vary across the age spectrum, and examine the potential causes of these disparities.…

Epigenetic Biomarkers of Prenatal Tobacco Smoke Exposure Are Associated with Gene Deletions in Childhood Acute Lymphoblastic Leukemia

We assess the association between smoking and gene deletion using two epigenetic biomarkers for maternal smoking during pregnancy—DNA methylation at AHRR CpG cg05575921 and…

The Learning Curve for Shared Decision-making in Symptomatic Aortic Stenosis

This mixed-methods study included a nonrandomized pre-post intervention and clinician interviews.

Pragmatic Study of Clinician Use of a Personalized Patient Decision Aid Integrated into the Electronic Health Record: An 8-Year Experience

This pragmatic study examines use of PDAs integrated into the electronic health record over an 8-year period.

Timing of Electronic Health Record Integrated Decision Aid (Idea) for Stroke Prevention in Atrial Fibrillation Matters

a cluster randomized trial

Does a Telehealth “Virtual Consult” Including Referring Physicians, Specialist Physicians and Patients Increase Shared Decision Making for Patients With Heart Disease?

This study utilized telehealth to bring referring physicians and their patients together with a specialist physician to exchange treatment options and patient preferences…

a Learning Curve for Shared Decision Making

The Impact of Physician Experience on Decision Aid Efficacy in Severe Aortic Stenosis

Perceived Future Epilepsy Risk Among Unaffected Members of Multiplex Epilepsy Families

my master thesis project